Posts tagged with effect

There is a certain hype about mixed (and random) effects among statistician and analysts. You can show some love to Douglas Bates and Martin Maechler for maintaing the lme4 package for our cupid, R ;)

I copy the entity of the information of the projects page.

Doxygen documentation of the underlying C functions is here.

The project summary page you can find here.

References to articles and other research using nlme or lme4 can be found here. The LaTeX bibliography file can be accessed from here. If you would like to add your work to this database, please email vasishth.shravan at gmail dot com

Slides from short courses on lme4 are here.

Chapter drafts of the book lme4: Mixed-effects Modeling with R are available here.

To complete this quick post, I append the following vignettes.

Implementation Details
PLS vs GLS for LMMs
Computational Methods

[source]

So, back in September I had a -temporary I must admit- interest on clinical trials and I cared enough to scroll screens in order to read the following Wired’s post,

Placebos Are Getting More Effective. Drugmakers Are Desperate to Know Why.

The placebo effect is of the most provocative mysteries of medicine, raising questions about the role of belief and expectation in healing. At the same time, positive response to the fake drugs used as controls in clinical trials of new drugs seems to be growing stronger worldwide. This is causing a crisis in the development of treatments for depression, anxiety, Parkinson’s, chronic pain, and other ailments, as more experimental drugs fail in late-stage tests. Merck’s William Potter, placebo pioneer Fabrizio Benedetti, Columbia researcher Tor Wager, and Harvard’s Ted Kaptchuk talk about the biological foundations of the body’s self-healing networks, the role that advertising may be playing in the rise of the placebo effect, and a new under-the-radar effort by companies like Merck and Lilly to understand why so many drugs are struggling to prove themselves more effective than sugar pills. (source)

Not much to argue about right? There’s a Mind Hack take on the theme too.

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